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Symptoms towards end of life pain. extreme tiredness (fatigue) problems with diet and digestion. weight loss and reduced appetite. feeling and being sick. a blocked duodenum. stomach emptying slowly. bowel problems.
What methotrexate does to the body?
Methotrexate is in a class of medications called antimetabolites. Methotrexate treats cancer by slowing the growth of cancer cells. Methotrexate treats psoriasis by slowing the growth of skin cells to stop scales from forming. Methotrexate may treat rheumatoid arthritis by decreasing the activity of the immune system.
How expensive is Spinraza?
Spinraza list price in the USA is US$125,000 per injection which puts the treatment cost at US$750,000 in the first year and US$375,000 annually after that. According to The New York Times, this places Spinraza "among the most expensive drugs in the world".