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There are three approaches to the treatment of dystonia, depending on the region of the body affected and the severity of the symptoms: medications, botulinum toxin injections and surgery.
This patient is at high risk for cognitive toxicity due to this anticholinergic burden and he or she is also at high risk for developing frank delirium if another drug with significant anticholinergic activity (eg, diphenhydramine) is added to this regimen (either by self-administration or as per the instruction of his or her prescribing healthcare provider).
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Clemastine is an antihistamine with and effects.
Be alert to nonverbal clues and supplement interactions with a communication board, mechanical voice synthesizer, computer, or electric typewriter.
Usually, Parkinson disease begins subtly and progresses gradually.
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Many cities have support groups that can be located through the United Cerebral Palsy Association, and most large medical centers have special multidisciplinary clinics for children with developmental disorders.
The US once had a tabun production program, which ended many decades ago.
The dopamine agonist pramipexole (Mirapex, generic) may also be helpful for Parkinson depression.
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Purple mottling of the skin (livedo reticularis) can be a side effect, along with hallucinations.
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In 1973, neurologist Oliver Sacks published Awakenings, an account of his work in the late 1960s with surviving post-encephalitic patients in a New York hospital.
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Also known as first-generation or typical antipsychotics, this class of drugs was discovered and used in practiced before the atypical drugs were discovered.
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The National Alliance on Mental Illness (NAMI), a patient- and family-oriented self-help group, has designated schizophrenia a brain disorder, emphasizing that schizophrenia is not simply a product of dysfunctional parenting or other psychosocial stressors.
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Debate continues about which of these subtypes are important in the initial pathophysiology of Parkinson's disease, the eventual development of motor fluctuations and the occurrence of pharmacologic side effects.
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TD, a host of dopamine and norepinephrine antagonists in addition to those already discussed above have been tested for potential antidyskinetic effects.
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With the use of entacapone dyskinesias may become more prominent and a corresponding reduction in levodopa dosing is indicated.
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The Parkinson-inducing effects of MPTP were first discovered following accidental ingestion as a result of contaminated MPPP.
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Multifocal dystonia involves two or more unrelated body parts.
Using structured questionnaires, Amselem et al determined that 61 out of 596 women (10%) attending a gynecologic clinic had pelvic floor damage; constipation was present in 19 of the 61 (31%), rivaling the frequency of obstetric trauma (also 19 women) among these patients.
Since younger patients seem to be at a higher risk of levodopa-related motor complications, delaying levodopa therapy seems to be a prudent practice at least in this population of PD patients.
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The advice and intervention of various professionals remains crucial for many people with CP.
Older adults may be more sensitive to the side effects of this drug, especially QT prolongation (see above), drowsiness, confusion, constipation, or trouble urinating.
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Parkinson's disease tremor is available and includes oral medications, botulinum toxin injections, and deep brain stimulation surgery.
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Conditions associated with non-motor impairment symptoms of Parkinson disease may need a variety of treatments.
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Factors that contribute to obesity and diabetes in these patients include unstable lifestyle, low social economic status, and side effects of any antipsychotic medications.
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Subsyndromal psychotropic side effects (eg, sleep disturbances, sexual dysfunction, fatigue, dysphoria, impaired concentration, decreased alertness, deficits in verbal memory, and mental slowing) are probably more prevalent than the psychiatric syndromes described above, though they have not been well studied.
Proof of this is the response to the most selective serotonin reuptake inhibitor, citalopram.
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