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Thanks for everyone's reviews. I have been suffering through so many of the same menopausal symptoms. Had Doctor's appointment today and just cannot take it any longer. Hot flashes, no sleep, irritability, anxiety, heart palpitations and many more. Excited to give estradiol (mist-spray form) and Prometrium a try...wish me luck.

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Have had no hot flushes since using Estradiol Valerate. Does a very good job reducing hot flashes. After less then I week, I've had only mild hot flashes and 2 good nights of sleep. I'm so happy to be taking Estradiol Valerate. No side effects, it's easy to use, is plant based and does not go through the liver. Simply wonderful

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