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Do cortisol levels increase at night? Blood levels of cortisol vary throughout the day, but generally are higher in the morning when we wake up, and then fall throughout the day. This is called a diurnal rhythm. In people that work at night, this pattern is reversed, so the timing of cortisol release is clearly linked to daily activity patterns.
Who diagnose Addison's disease? Measuring cortisol and ACTH levels can help determine if adrenal insufficiency is present, and if so, whether the problem is with the adrenal glands or brain. An evaluation of Addison's disease can include a CT scan of the adrenal glands to look for infection, cancer, or bleeding in the adrenal glands.
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