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Can you overdose on orphenadrine? An overdose of orphenadrine can be fatal. Overdose symptoms may include blurred vision, fast heart rate, confusion, weak or shallow breathing, cold or clammy skin, feeling like you might pass out, or seizure (convulsions).
What are triptans and Ergots? Triptans and MAOIs The enzyme monoamine oxidase (MAO) breaks down some or all of four triptans : almotriptan (Axert), rizatriptan (Maxalt), sumatriptan (Imitrex), and zolmitriptan (Zomig). At the same time, some antidepressants can be used as anti-migraine drugs and work by inhibiting MAO (MAOIs).